This is arguably outside the normal realm of this blog, as it was published by ACG in 1954. During a brief era of popularity for 3-D comics, ACG came up with an interesting process that didn't require glasses.
As you can see, the result was visually pleasing:
The effect used several tricks. First, the extension of the drawings outside the frame appears more obvious with the black pages. Second, people are drawn in bright colors while backgrounds are pastels or light greys. Not terribly difficult but it was a nice break from the glasses of the era.